Epilepsies are most common serious neurological disorders affecting 50 million people of all ages globally. Epilepsy should not be regarded, however, as one specific disease entity as it associates with and/or results from many aetiologies, ranging from single genetic point mutations, to metabolic dysfunction or acquired brain lesions. Indeed, any brain can generate seizures and any lesion may lower the brain’s seizure threshold. During their last executive board meeting in February 2015, WHO has acknowledged the global burden of epilepsy and the need for coordinated action at the country level to address its health, social and public knowledge implications. Click links for further information about epilepsy and WHO initiatives.